Biological modulation for endometriosis and adenomyosis

A formula designed around clinically validated biological mechanisms

ENDORA™ is a synergy of active compounds, each supported by scientific research, designed to act across multiple biological pathways.

Key active ingredients

PAM™ COMPLEX (EGCG · Apigenin · Luteolin) · N-acetyl-L-cysteine · Micronized resveratrol · Boswellin® Forte · 3,3′-Diindolylmethane (DIM) · Zinc · Vitamin D3

Biological Mechanisms

Why do
endometriosis and adenomyosis persist?

These conditions may persist due to complex mechanisms that can reinforce one another. An approach that accounts for multiple biological pathways may therefore be relevant.

01 bloodtype

Formation of new blood vessels

Endometrial tissue growing outside its natural location can develop its own blood supply for nutrients and oxygen, which may allow lesions to persist.

02 published_with_changes

Impaired apoptosis

Ectopic endometrial cells may evade the normal programmed cell death at the end of the cycle, allowing them to survive and continue proliferating.

03 female

Local estrogen production

Lesions may produce their own estrogen, sustaining an inflammatory environment even when systemic hormone levels are balanced.

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Chronic inflammation

A self-perpetuating cycle may exist in which inflammation generates mediators that further amplify inflammation, contributing to discomfort and disease progression.

A Unifying Perspective

Endometriosis and adenomyosis:
different in location, biologically aligned

Although conventional medicine often treats them as distinct conditions due to their anatomical location, molecular research confirms that both represent expressions of the same underlying dysfunction.

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Endometriosis

Defining characteristics

  • check Endometrium-like tissue present outside the uterus (ovaries, fallopian tubes, peritoneum)
  • check Typically manifests as severe cyclical pelvic pain and often infertility
info Extrauterine location
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Adenomyosis

Defining characteristics

  • check Infiltration of endometrial tissue into the uterine muscular wall (myometrium)
  • check Typically presents with an enlarged, globular uterus and heavy menstrual bleeding
info Intrauterine location

Shared biological mechanisms

What connects these two conditions at the cellular level

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Chronic inflammation

Persistent inflammatory activity within tissues

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Estrogen dominance

Imbalance within the local hormonal environment

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Apoptosis resistance

Cells fail to undergo normal end-of-cycle cell death

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Angiogenesis

Formation of new blood vessels to support tissue growth

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Regardless of location, both conditions respond to the same strategy: reducing inflammation and modulating the hormonal environment.

A unified approach for shared biological mechanisms

Scientific Formulation

Biological architecture
ENDORA™

ENDORA™ is built on a functional architecture designed to address multiple mechanisms involved in endometriosis and adenomyosis simultaneously.

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PAM™ COMPLEX

A proprietary proliferation-modulating matrix, targeting signaling pathways involved in angiogenesis and cell-cycle regulation.

Primary focus
Proliferation control & apoptosis
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Redox & inflammation

Helps balance inflammatory signaling and oxidative stress, supporting a more stable pelvic microenvironment.

Primary focus
Immuno-inflammatory modulation
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Metabolism & support

Supports liver function for estrogen metabolism and optimizes cellular metabolism.

Primary focus
Estrogen metabolism
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PAM™ COMPLEX

The innovation core of ENDORA™, a synergistic flavonoid trio:

  • 01

    EGCG (Epigallocatechin Gallate)

    Green tea extract (98% polyphenols). Involved in angiogenesis modulation.

  • 02

    Apigenin

    A flavonoid involved in cell-cycle regulation.

  • 03

    Luteolin

    A flavonoid implicated in multiple cellular signaling pathways.

Active compounds

N-Acetylcysteine (NAC)

Pharmaceutical-grade

A glutathione precursor that supports redox balance in the context of chronic inflammation.

Trans-Resveratrol

Micronized

Micronized form for enhanced absorption, contributing to modulation of inflammatory signaling.

Boswellin® Forte

15% AKBBA

A standardized extract involved in modulation of inflammatory signaling.

DIM (Diindolylmethane)

Cruciferous

Involved in estrogen metabolism in the context of estrogen dominance.

Zinc Monomethionine

Chelated

An essential micronutrient supporting enzymatic function, immunity, and cellular integrity.

Vitamin D3

Cholecalciferol

Involved in immune response regulation in the context of chronic inflammation.

Other ingredients

Vegetable capsule (Pullulan). The formulation contains no additives or excipients.

Usage Guide

Usage protocol
ENDORA™

A food supplement designed to provide comprehensive biological support. Consistent use and adherence to the recommendations matter for achieving the intended outcomes.

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medication

Daily intake

For consistent support, daily intake helps maintain a steady supply of active ingredients.

  • check_circle 2 capsules per day, preferably in the morning after a meal.
  • check_circle Take with a full glass of water.
  • check_circle Recommended duration of use: at least 30 days.
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Recommended duration

For a complex food supplement such as ENDORA™, it is important to follow a sufficiently long intake period to allow the body to benefit from the active compounds.

Month one

Starting

Adjustment and familiarization with the complex formula.

Month two

Continuing

Consistent support for the body’s processes.

Month three

Consolidation

Sustained support toward the expected benefits.

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Integration recommendations

A balanced lifestyle

Food supplements work best within a healthy lifestyle context, including balanced nutrition and stress management.

Regular consultations

For any questions related to supplementation, always consult a healthcare professional.

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Usage Profile

Who ENDORA™ is for

Formulated to support biological mechanisms involved in chronic inflammatory processes associated with women’s health.

Endometriosis & Adenomyosis

For women facing chronic inflammatory processes associated with endometriosis or adenomyosis and looking for complementary biological support.

Polycystic Ovary Syndrome (PCOS)

Supports metabolic and hormonal balance in the context of PCOS, especially when associated with low-grade inflammation.

Dysmenorrhea & Premenstrual Syndrome

For women with pronounced menstrual discomfort, providing support for balancing the inflammatory processes involved.

Recovery & Support

Can be integrated as nutritional support during recovery periods or increased biological demand, within a balanced lifestyle.

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Who ENDORA™ is not recommended for

ENDORA™ is intended for adult use. It is not recommended for:

  • close Pregnant or breastfeeding women
  • close Individuals with allergies to any ingredient in the formula
  • close Use alongside certain hormonal therapies without medical guidance
medical_information

Individual assessment

Notice: In situations such as pregnancy, breastfeeding, or ongoing hormonal therapies, consulting a healthcare professional before use is recommended.

Personalized Guide

Quiz: Is ENDORA™ right for you?

Answer a few simple questions to see how ENDORA™ may support your situation.

Progress Step 1 of 5
Question 1

Have you been medically diagnosed with endometriosis or adenomyosis?

Question 2

Which symptoms are frequently present for you?

Select all that apply:

Question 2

Do you have menstrual pain that affects your daily activities?

Question 3

Are your symptoms cyclic (around your period)?

Question 4

How long have these symptoms persisted?

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Profile consistent with adjuvant biological support

ENDORA™ is formulated to support biological mechanisms involved in chronic inflammation, angiogenesis, and estrogen metabolism, as part of an integrated management approach.

lightbulb Recommendation

Discuss integrating ENDORA™ as a food supplement with your treating physician for a personalized approach.

Clarifications

Frequently asked questions

Evidence-informed answers about the ENDORA™ formula, mechanisms of action, and how to integrate it into your daily routine.

What is the difference between endometriosis and adenomyosis, and how does ENDORA™ support both?

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Endometriosis is characterized by endometrial-like tissue located outside the uterus, while adenomyosis involves infiltration of this tissue into the muscular wall of the uterus. Although anatomically distinct, both conditions share common biological mechanisms, including chronic inflammation and oxidative stress.

ENDORA™ is designed to support the biological mechanisms involved in these processes. Its active ingredients are selected to provide comprehensive support in the context of endometriosis-related conditions.

Is a full 3-month cycle necessary?

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For a complex food supplement like ENDORA™, consistent intake over a sufficiently long period is recommended to allow the body to benefit from the full spectrum of active compounds.

A minimum 3-month cycle is suggested to provide continuous support for the biological processes involved. Consistency matters for the intended outcomes.

What makes the PAM™ complex unique in the formula?

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PAM™ (Phyto-Active Modulation) is the proprietary matrix combining EGCG, Apigenin, and Luteolin in a synergy designed to address multiple cellular signaling pathways involved in inflammatory processes.

This combination is selected for its synergistic potential in providing comprehensive support at both tissue and cellular levels.

Can I take ENDORA™ if I’m on hormonal therapy?

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ENDORA™ is a food supplement without hormones and is designed to be complementary to other approaches. In any situation involving complex medical treatment, consult your physician before adding any new supplement to your routine.

For optimal use, consider keeping a gap of a few hours between supplements and medications.

Are there contraindications or side effects?

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ENDORA™ is formulated with natural ingredients and has a generally favorable safety profile. It is not recommended for pregnant or breastfeeding women due to the lack of specific studies in these populations.

At the beginning of use, some individuals may notice minor adaptation effects. If symptoms persist or concern you, discontinue use and consult a physician.

How does it fit with an anti-inflammatory diet?

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A balanced diet rich in anti-inflammatory foods is a foundation for overall health. ENDORA™ can complement these choices by providing concentrated, selected active ingredients.

These two approaches—nutrition and supplementation—can work together to provide broader support in managing inflammatory processes.

Is it suitable for Polycystic Ovary Syndrome (PCOS)?

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Yes, ENDORA™ can be considered as complementary support in the context of PCOS. The formula addresses multiple relevant mechanisms, including those linked to metabolic and hormonal balance.

The selected ingredients are chosen for their potential to support biological processes relevant to women’s health.

Why does ENDORA™ work?

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ENDORA™ is formulated based on existing clinical studies on the individual ingredients, complemented by observational data and in vitro research in human cells. Each ingredient is selected for demonstrated biological mechanisms—such as inflammation, oxidative stress, angiogenesis, and hormonal metabolism—and used at clinically investigated doses. The formula is built for mechanistic synergy, with compounds acting on complementary and convergent pathways to support an integrated biological effect.